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KMID : 0861220090110020067
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Journal of the Korean Society Clinical Neurophysiology
2009 Volume.11 No. 2 p.67 ~ p.70
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Colchicine Induced Myopathy Presenting Electrophysiologic Myotonia
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Yang Ji-Won
Kim Na-Rai
Park Kee-Hyung
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Abstract
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Colchicine is widely used in the treatment of gouty arthritis, and chronic use of colchicine can cause vacuolar myopathy. We report colchicine-induced myopathy with electrophysiological myotonia in a patient with gouty arthritis. A 86-year-old man with gouty arthritis presented with progressive proximal weakness and gait disturbance. Electrophysiological finding showed myotonic myopathy and muscle biopsy revealed a vacuolar myopathy. His symptoms soon resolved with the discontinuation of colchicine.
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KEYWORD
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Cochicine, Myotonia, Gout
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